Henderson features an attractive array of industrial and commercial locations to meet the needs of expanding and/or relocating businesses. Three industrial zoning designations are currently utilized in Henderson to provide a broad range of opportunities for light manufacturing, research and development, warehouse/distribution, and service uses: IP - Industrial Park District, IL - Limited Industrial District, and IG - General Industrial District. Henderson also features a full range of possible commercial locations for corporate office, call center, retail, and service uses.
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Henderson - Major Business Parks and Retail Corridors
| Business Parks | Major Tenants/Projects | Available Buildings |
| 1) Gibson Business Park | Ocean Spray Cranberries, Inc., Pacific Business Center, Suncrest Commerce Center | Yes |
| 2) Black Mountain Business Park | Black Mountain Corporate Center, Graham Packaging Company, Quality Corrections & Inspections, Touro University - Nevada | Yes |
| 3) Traverse Point Center | Traverse Point Commerce Center | Yes |
| 4) Green Valley Business Park, Whitney Mesa Business Park | AllenTel Products, Ethel M Chocolates, Roseman University of Health Sciences | Yes |
| 5) Henderson Executive Airport Center, South 15 Airport Center, Limited Transition Area (LTA) | Henderson Quail Air Center, Levi Strauss & Co., South 15 Airport Center, VNE Jet | Yes |
| 6) Conestoga Industrial Area | Poly West, Flowers Foods | Yes |
| 7) Cornerstone | Nevada Orthopedic & Spine Center | Yes |
| 8) Eastside and Sunpac Industrial Areas | Armand Manufacturing, Advanced Superabrasives, Inc. | Yes |
| 9) Black Mountain Industrial Center | Pro-Caps Laboratories | Yes |
| 10) Henderson Commerce Center | Las Vegas Distillery, ParPro | Yes |
| 11) Green Valley Corporate Center | American Nevada Company, The Art Institute of Las Vegas, Barclays, Barrick Gold, ITT Technical Institute, Vegas.com | Yes |
| 12) Green Valley Corporate Center South | Amica, DeVry University, Toyota Financial Services | Yes |
| 13) Siena Office Park | Western Regional Center for Brain & Spine | Yes |
| Major Retail Corridors |
| 1) St. Rose Parkway & Eastern |
| 2) Sunset & Green Valley Parkway |
| 3) Galleria Mall Area - Sunset & Stephanie to Warm Springs & Marks |
| 4) Boulder Highway & Lake Mead Drive |
| 5) The District at Green Valley Ranch |
| 6) Montelago Village at Lake Las Vegas |